Institute of Psychiatry at the Maudsley
KCTU | King's Clinical Trials Unit
Study Index v1.4

Update Lists
Randomisation Projects - Live
  ACTIB Assessing Cognitive behavioural Therapy in Irritable Bowel ISRCTN44427879
  ACTMUS Acceptance and Commitment Therapy for Muscle Disease NCT02810028
  ADAPT Atopic Dermatitis Anti-IgE Paediatric Trial ISRCTN15090567
  AerosureCF A short – term comparative study of Aerosure for airway clearance in patients with cystic fibrosis NCT01923753
  AerosureCOPD Does high-frequency airflow oscillation, delivered using Aerosure, increase exercise capacity in severe chronic obstructive pulmonary disease? NCT02007590
  AMBITION mindfulness-based crisis interventions (MBCI) for psychosis within acute inpatient psychiatric settings; a feasibility randomised controlled trial ISRCTN37625384
  APIPPRA_NETHERLANDS Arthritis Prevention In the Pre-clinical Phase of RA with Abatacept (APIPPRA) ISRCTN46017566
  APIPPRA_UK Arthritis Prevention In the Pre-clinical Phase of RA with Abatacept (APIPPRA) ISRCTN46017566
  APRICOT Treatment of pustular psoriasis with the IL-1 receptor antagonist anakinra: a randomised, placebo controlled trial and associated mechanistic studies 2015-003600-23
  ASCOT A phase 3 multi-center double masked randomised controlled trial of adjunctive intraocular and periocular steroid (triamcinolone acetonide) versus standard treatment in eyes undergoing viteroretinal surgery for open globe trauma ISRCTN30012492
  AVATAR Reducing the frequency and severity of auditory hallucinations: the AVATAR clinical trial ISRCTN65314790
  BeMind A comparison to two types of group behaviour therapy for obsessive compulsive disorder: A pilot randomised controlled trial of behaviour therapy and mindfulness-based behaviour therapy for OCD ISRCTN52684820
  CADMUS Multi-parametric Ultrasound targeted biopsies compared to Multiparametric MRI targeted biopsies in the diagnosis of clinically significant prostate cancer NCT02712684
  CALLME Care Augmentation by Location-Linked Messaging ISRCTN71271888
  CASAAF Catheter Ablation vs. Thoracoscopic Surgical Ablation in Long-Standing Persistent Atrial Fibrillation ISRCTN18250790
  CBDVR2 The effect of CBD on paranoid cognitions in humans ISRCTN11082858
  CBMpa Cognitive Bias Modification for Paranoia ISRCTN90749868
  CIAOII Randomised controlled trial of the short term effects of OROS-methylphenidate on ADHD symptoms and behavioural outcomes in young male prisoners with attention deficit hyperactivity disorder ISRCTN16827947
  CICADA Inhibiting white blood cell function as a new way to treat coronary heart disease ISRCTN48328178
  CLARITY Clinical Efficacy and Mechanistic Evaluation of Aflibercept for Proliferative Diabetic Retinopathy (CLARITY). A Multicentre Phase IIb Randomised Active-Controlled Clinical trial. ISRCTN32207582
  CODES COgnitive behavioural therapy vs standardised medical care for adults with Dissociative non-Epileptic Seizures: A multicentre randomised controlled trial ISRCTN05681227
  CONVINCE A study to assess the feasibility and patient acceptability of a randomised, crossover design to compare virtual vs conventional chromoendoscopy for the detection of dysplasia in colitis NCT02543021
  CRiB Cognitive Remediation in Bipolar disorder: a feasibility study ISRCTN32290525
  CUESPLUS Coping with Unusual ExperienceS for 12-18 year olds ISRCTN21802136
  DATES Diabetes And Telecommunications Study to support self-management for people with type 2 diabetes: a randomized controlled trial(The DATES trial) ISRCTN10342151
  DFEND A randomised, double-blind, placebo-controlled, parallel-group trial of Vitamin D supplementation compared to placebo in people presenting with their First Episode of psychosis Neuroprotection Design (DFEND) 2014-002639-32
  DiabetesStopwatch Effectiveness of integrating motivational instant messaging into an e-diabetes prevention programme in people at high risk of type 2 diabetes: a prospective, parallel-group, randomised controlled trial NCT02919397
  ECLIPSE ECLIPSE Study 9: Building resilience and recovery through enhancing cognition and quality ISRCTN14678860
  ENPENS A randomised patient-assessor blinded sham controlled trial of External non-invasive peripheral nerve stimulation for chronic neuropathic pain following peripheral nerve injury (EN-PENS trial). ISRCTN53432663
  EPACS Early Prolonged Ambulatory Cardiac monitoring in Stroke ISRCTN50253271
  FORSUS Comparison of the effectiveness of the Twin Block and FORSUS functional appliance for the treatment of Class II division 1 malocclusion patients ISRCTN80447398
  FRAMEFIT Frame Fit. A randomised controlled trial to determine the acceptability, safety and efficacy of a falls prevention exercise programme for walking frame users. ISRCTN57645734
  GLIDE Gastric Band and Liraglutide Intervention in Diabetes Evolution – A Randomised Double-Blind Plcaebo-Controlled Trial ISRCTN10551314
  HFPRCT Helping Families: Psychoeducational Intervention for Parents with Personality Disorders ISRCTN14573230
  HOTKID The Hypertension Optimal Treatment in Children with Chronic Kidney Disease study: The HOT-KID study- A randomised trial to compare effects of aggressive versus standard targets in blood pressure on target organ damage in children with CKD’ ISRCTN25006406
  IMAGINE A brief early intervention for adolescent depression that targets emotional memories: a feasibility randomised controlled trial ISRCTN85369879
  InterMuscle A Phase 2 Pilot Physiological Randomised Clinical Trial to Investigate the Effect of Intermittent versus Continuous Enteral Nutrition on Muscle Wasting in Critical Illness NCT02358512
  INTERSTAARS Attention Control Training for Infants at Risk for ADHD ISRCTN37683928
  IPTG01 An antimicrobial cream for the treatment of impetigo 2008-000036-41
  LEAVO A Multicentre Phase III Double-masked Randomised Controlled Non-Inferiority Trial comparing the clinical and cost effectiveness of intravitreal therapy with ranibizumab (Lucentis) vs aflibercept (Eylea) vs bevacizumab (Avastin) for Macular Oedema due to Central Retinal Vein Occlusion (CRVO). ISRCTN13623634
  LIFT Prospective randomised marker-based trial to assess the clinical utility and safety of biomarker-guided immunosuppression withdrawal in liver transplantation ISRCTN47808000
  LIPS Low dose intravenous immunoglobulin treatment for complex regional pain syndrome 2012-000058-73
  LQD Lithium versus quetiapine in treatment resistant depression ISRCTN16387615
  MAGSTAR MAGnetic versus STAndard technique for sentinel node biopsy in breast cancer compared in a Randomised controlled trial ISRCTN20200149
  METAL Metformin and Longevity: A window of opportunity study investigating the biological effects of metformin in localised prostate cancer 2014-005193-11
  MIFCOG Cortisol and memory in alcoholics: Mifepristone Study ISRCTN54001953
  MINDEP Understanding the molecular basis for the use of adjunctive anti-inflammatory treatment in treatment resistant depression: a stratified, randomised, placebo-controlled, experimental medicine study using minocycline 2015-003413-26
  MOLTO Single arm feasibility of multi-maintenance olaparib after disease recurrence in participants with platinum sensitive BRCAm high grade serous ovarian cancer NCT02855697
  MYPS1 Mycophenolate Treatment for Longstanding Complex Regional Pain Syndrome. 2015-000263-14
  NEAT Naltrexone Enhanced Addiction Treatment for opioid dependence. A randomised controlled trial of the clinical and cost-effectiveness of implanted extended-release naltrexone and oral naltrexone 2013-002584-25
  NeuroMooD Comparing fMRI neurofeedback and neurostimulation treatments in self-blaming emotions in major depressive disorder – a pilot trial ISRCTN10526888
  NOC The NOC Study (Nitric Oxide in Cognition) NCT02906553
  NOStudy The effect of nitric oxide on spatial working memory in patients with schizophrenia – pilot study NCT02176044
  OPTCare_Elderly OPTCare Elderly - Optimising palliative care for older people in community settings: a feasibility study developing and evaluating a new short term integrated service ISRCTN45837097
  OPTCare_Neuro Evaluation of the clinical and cost-effectiveness of Short-term Integrated Palliative Care Services (SIPC) to OPTimise CARE for people with advanced long-term Neurological conditions ISRCTN18337380
  OUTSMART Optimized TacrolimuS and MMF for HLA Antibodies after Renal Transplantation ISRCTN46157828
  PACT A randomised controlled trial of brief physiotherapy informed by Acceptance and Commitment Therapy for chronic low back pain : the PACT study ISRCTN95392287
  PACTG Improving autistic children's social communication with parents in everyday settings ISRCTN25378536
  PAVE Paclitaxel assisted balloon Angioplasty of Venous stenosis in haEmodialysis access ISRCTN14284759
  PAZOFOS A phase Ib and Randomised Phase II Trial of Pazopanib with or without Fosbretabulin in Advanced Recurrent Ovarian cancer NCT02055690
  PEACE Comparison of Trabeculectomy with Mitomycin-C versus Baerveldt tube surgery with and without Mitomycin-C in black African/African-Caribbean patients with primary open angle glaucoma: a randomised feasibility trial NCT02989207
  PET Outcome following Stabilization of fresh unilateral unstable pertrochanteric hip fracture with either the Endovis BA2 cephalomedullary nail or the Dynamic Hip screw: A Single Centre, Feasibility Study NCT02788994
  preheat PREHEAT Trial - local heat preconditioning and wound healing ISRCTN15744669
  PRESERVE How intensively should we treat blood pressure in established cerebral small vessel disease? ISRCTN37694103
  PRINCEPrimary Persistent physical symptoms Reduction INtervention: a system Change & Evaluation in Primary Care (PRINCE Primary) NCT02444520
  PRINCESecondary Persistent Physical Symptoms Reduction Intervention: a System Change and Evaluation in Secondary Care NCT02426788
  PRISM A Prospective Randomised Study of Advanced Imaging Guided Cardiac Resynchronisation Therapy (CRT) vs Conventional CRT Implantation in Patients with Chronic Heart Failure NCT01429753
  RADICRT A Prospective Randomised Controlled Trial of Cardiac Resynchronisation Therapy Guided by Invasive dP/dt: Radi-CRT Study NCT01464502
  REDUCe Palliative long-term abdominal drains versus repeated drainage in individuals with untreatable ascites due to advanced cirrhosis: a feasibility randomised controlled trial ISRCTN30697116
  RESTUS A randomised feasibility study examining daily sedation holds and nocturnal rest using neurally-adjusted ventilatory assist (NAVA) in patients at high risk of prolonged ventilatory failure during recovery from critical illness NCT01826890
  ReZone Developing an app to help young people self-manage when feeling overwhelmed during lessons ISRCTN13425994
  SCIN SCIN (Skin care intervention in nurses) Trial ISRCTN53303171
  SITADS Pilot randomised controlled trial of SITAgliptin for Depressive Symptoms in type 2 diabetes 2015-004527-32
  STAR StereoTactic radiotherapy for wet Age-Related macular degeneration (STAR): A randomised, double-masked, sham-controlled, clinical trial comparing low-voltage X-ray irradiation with as needed bevacizumab, to as needed bevacizumab monotherapy. NCT02243878
  STRIVE A multicentre randomiSed controlled TRial of IntraVEnous immunoglobulin (IVIg) versus standard therapy for the treatment of transverse myelitis in adults and children ISRCTN12127581
  STRIVEHF Standard Care vs Trtiventricular Pacing in Heart Failure NCT02529410
  SUPA SUPA: Supporting UPtake and Adherence to antiretrovirals Applying the Medical Research Council guidance to evaluate an intervention to support uptake and adherence to antiretroviral therapy for HIV ISRCTN35514212
  SWAN A two arm feasibility trial of lifestyle information and Slimming World groups to promote weight management and positive lifestyle behaviour in postnatal women from an ethnically diverse inner city population ISRCTN39186148
  TIARA A sham-controlled randomised feasibility study of repetitive transcranial magnetic stimulation (rTMS) as an adjunct to treatment as usual in adults with severe and enduring anorexia nervosa (SE-AN). ISRCTN14329415
  TiMM The role of apixaban, aspirin and enoxaparin as Thromboprophylaxis in patients newly diagnosed with Multiple Myeloma - an open label randomised control clinical trial - TiMM 2015-002668-18
  TITRATE A pragmatic randomised controlled open trial of the effect of intensive management (IM) compared with standard care (SC) on remission rates at 12 months in rheumatoid arthritis patients with intermediate disease activity ISRCTN70160382
  TOHETI A single centre randomised, nonblinded, prospective trial to evaluate the use of MRI as the initial imaging modality in the investigation of patients presenting with suspected scaphoid fracture. NCT02801149
  UREDIA The renoprotective effects of Ursodeoxycholic acid in patients with type 1 diabetes and macroalbuminuria 2015-003609-41
  VitaminK The Additive effect of Vitamin K Supplementation and Bisphosphonate on Fracture Risk in Post-menopausal Osteoporosis NCT01232647
  WENDY A cross-sectional study comparing the Whooley questions and Edinburgh postnatal depression scale against a diagnostic assessment in identifying depression in pregnancy 16403
Randomisation Projects - In Development
  AMBIC Abbreviated Mentalization Based Therapy in Borderline Crises
  HARPdoc Beyond education: A Hypoglycaemia Awareness Restoration Programme for people with type 1 diabetes and problematic hypoglycaemia persisting despite optimised self-care (HARPdoc) NCT02940873
  HYPATIA HYPATIA: A prospective randomised controlled trial of HYdroxychoroquine versus placebo during Pregnancy in women with AnTIphospholipid Antibodies
  LAST Effect of Lixisenatide on arterial stiffness in patients with diabetic nephropathy
  TRIANGLE A multicentre randomised controlled trial to examine whether the addition of a patient and carer skills-sharing intervention improves long-term patient wellbeing following hospital treatment for anorexia nervosa. ISRCTN14644379
Randomisation Projects - Completed
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  ACTfR ACT for Recovery ISRCTN68540929
Therapy Rating Projects
  Codes COgnitive behavioural therapy vs standardised medical care for adults with Dissociative non-Epileptic Seizures: A multicentre randomised controlled trial
  CONMAN1 Developing a UK Evidence Base for Contingency Management in Addiction Treatment: Incentive-based interventions to improve treatments to reduce drug use and associated harms
  NOURISHED A Randomized Controlled Trial of Mentalization Based Therapy against Treatment as Usual in patients with both Eating Disorders and Borderline Personality Disorder
  PRAISeAbstinence Postive Reinforcement targeting Abstinence In Substance misusE (PRAISE CM Abstinence)
  PRAISeAttendance Postive Reinforcement targeting Abstinence In Substance misusE (PRAISE CM Attendance)
  PRAISeSupervisor Postive Reinforcement targeting Abstinence In Substance misusE (PRAISE Supervisor)
  SOP For SOP documentation
  Titrate A pragmatic randomised controlled open trial of the effect of intensive management (IM) compared with standard care (SC) on remission rates at 12 months in rheumatoid arthritis patients with intermediate disease activityy
Other Projects
  FileUpload A custom file upload service to support the exchange of files
  Codebook A tool that generates codebooks for MACRO database studies
  Quote A tool that produces emailed service quotes for CTU services
  Macro3UserRequests Macro v3 User Request Online Management Tools
  Codebook4 A tool that generates coodebooks for MACRO v4
  Macro4UserRequests Macro v4 User Request Online Management Tools
  NRPTools NCR | RFC | PID | SOP online tools
  Codebook4dev A tool that generates coodebooks for MACRO v4 Development
  Macro4_2UserRequests Macro v4 User Request Online Management Tools (database 2)
  Codebook4_2 A tool that generates coodebooks for MACRO v4 (database 2)
  wiki wiki for the kctu
Update Lists

Contact Details
Email: randomisation.request@kcl.ac.uk
Telephone: 0207 848 5282
Fax: 0207 848 5229